TOLLIP 抗体
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北京 101111
Quick Overview for TOLLIP 抗体 (ABIN371662)
抗原
See all TOLLIP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific to Human Tollip. Does not react to TLR2, TLR4, TLR6, TLR7, TLR8 and TLR10 recombinant proteins.
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产品特性
- Synonyms: Toll-interacting protein
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纯化方法
- Purified
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免疫原
- Recombinant Tollip.
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亚型
- IgG2a
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anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibody
TOLLIP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A5-2A3 unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 19-254) antibodyTOLLIP 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 1-274) antibodyTOLLIP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 221-250), (C-Term) antibodyTOLLIP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4409 unconjugated
anti-Toll Interacting Protein (TOLLIP) (C-Term) antibodyTOLLIP 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 224-243), (C-Term) antibodyTOLLIP 适用: 人 WB, IHC, IF, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 28-261) antibodyTOLLIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll Interacting Protein (TOLLIP) (AA 86-163) antibodyTOLLIP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western Blot. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TOLLIP (Toll Interacting Protein (TOLLIP))
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别名
- TOLLIP
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背景
- Toll like protein is a component of the signaling pathway of IL1 and Toll like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C terminus. It exists as a complex with IRAK1 in unstimulated cells. Upon IL1 signaling, Tollip binds to the activated IL1 receptor complex containing IL-1RI, IL-1RacP and the adapter protein MyD88, where it interacts with the TIR domain of IL-1RacP. MyD88 then triggers IRAK1 autophosphorylation, which in turn leads to the dissociation of IRAK1 from Tollip and IL-1RAcP.Synonyms: Toll-interacting protein
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基因ID
- 54472
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UniProt
- Q9H0E2
抗原
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