TIMP4 抗体
Quick Overview for TIMP4 抗体 (ABIN371661)
抗原
See all TIMP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody is specific to Human TIMP4.
-
产品特性
- Synonyms: TIMP-4, Tissue inhibitor of metalloproteinases 4, Metalloproteinase inhibitor 4
-
纯化方法
- Purified
-
免疫原
- Recombinant TIMP-4.
-
亚型
- IgG2a
-
-
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 32-224) antibody
TIMP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (C-Term) antibodyTIMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 31-224) antibodyTIMP4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (C-Term) antibodyTIMP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 174-224) antibodyTIMP4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 42-224) antibodyTIMP4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 161-224) antibodyTIMP4 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 30-224) antibodyTIMP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 48-74) antibodyTIMP4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22433 unconjugated
anti-TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 55-82), (Middle Region) antibodyTIMP4 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western Blot: Detects a band of approximately 26 kDa (predicted Mol. Weight: 26 kDa). Immunohistochemistry on Frozen Sections. Immunocytochemistry/Immunofluorescence: Use at 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- 100 mM Borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- TIMP4 (TIMP Metallopeptidase Inhibitor 4 (TIMP4))
-
别名
- TIMP4
-
背景
- The MMPs and TIMPs can be divided into two groups with respect to gene expression: the majority exhibit inducible expression and a small number are produced constitutively or are expressed at very low levels and are not inducible. Among agents that induce MMP and TIMP production are the inflammatory cytokines TNF alpha and IL1 beta. A marked cell type specificity is a hallmark of both MMP and TIMP gene expression (i.e. a limited number of cell types can be induced to make these proteins). Tissue Inhibitor of Metalloproteinases 4 (TIMP4) was identified by molecular cloning. TIMP4 shows 37 % amino acid identity with TIMP1 and 51 % homology with TIMP2 and TIMP3. TIMP4 is secreted extracellularly, predominantly in heart and brain tissue. It may function in a tissue specific fashion in extracellular matrix (ECM) homeostasis. TIMP4 has a strong inhibitory effect on the invasion of human breast cancer cells across reconstituted basement membranes suggesting that TIMP4 may have an important role in inhibiting primary tumor growth and progression. The human TIMP4 gene has the chromosomal location of 3p25.Synonyms: Metalloproteinase inhibitor 4, TIMP-4, Tissue inhibitor of metalloproteinases 4
-
基因ID
- 7079
-
UniProt
- Q99727
抗原
-
