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CD21 抗体

This anti-CD21 antibody is a 小鼠 单克隆 antibody detecting CD21 in FACS, IP 和 IHC (fro). Suitable for Pig.
产品编号 ABIN371308
发货至: 中国

Quick Overview for CD21 抗体 (ABIN371308)

抗原

See all CD21 (CR2) 抗体
CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

适用

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Pig

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD21 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

BB6-11C9-6
  • 特异性

    This antibody is specific to Porcine CD21 (Mr. 160 kDa). It stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues: 92-96 % in peripheral blood, 74-98 % in mesenteric lymph nodes, 97-100 % in ileal Peyer's patches (ILPP), 93-97 % in spleen, and 0 % in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation). Does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).

    产品特性

    Synonyms: EBV Receptor, CR2, C3DR, Complement Receptor type 2, Complement C3d Receptor,Epstein-Barr virus Receptor

    纯化方法

    Purified

    亚型

    IgG1
  • 应用备注

    Flow Cytometry. (Ref.2-3)Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2)Immunoprecipitation. (Ref.2)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

    别名

    CD21

    背景

    CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor

    基因ID

    1380

    途径

    Complement System
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