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LAMP1 抗体

This anti-LAMP1 antibody is a 大鼠 单克隆 antibody detecting LAMP1 in WB, FACS, IP, IHC (fro) 和 IEM. Suitable for 小鼠.
产品编号 ABIN371199
发货至: 中国

Quick Overview for LAMP1 抗体 (ABIN371199)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This LAMP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

克隆位点

1D4B
  • 特异性

    This antibody is specific to CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa).

    交叉反应 (详细)

    Species reactivity (tested):Mouse

    产品特性

    Synonyms: LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1, CD107Antigen-like Family Member A

    纯化方法

    Purified

    免疫原

    Plasma membrane fraction of mouse embryo NIH3T3 cell line. (Ref. 1)

    亚型

    IgG2a
  • 应用备注

    Flow cytometry: < / = 1 μg/10^6 cells. (Ref.5)Immunohistochemistry on Frozen Sections. (Ref.5)Immunoaffinity Chromatography. (Ref.2)Western blot. (Ref.5)Immunoprecipitation. (Ref.1,3)Immunoelectron Microscopy. (Ref.6)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a / LAMP1

    背景

    CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. (Ref.2) CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.3) LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. (Ref.4)Synonyms: CD107 Antigen-like Family Member A, LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1

    基因ID

    16783

    UniProt

    P11438

    途径

    Autophagy
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