Integrin beta 7 抗体
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北京 101111
Quick Overview for Integrin beta 7 抗体 (ABIN371135)
抗原
See all Integrin beta 7 (ITGB7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7). It recognises a conformational epitope on the heterodimer.
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产品特性
- Synonyms: Integrin beta-P, M290 IEL antigen, ITGB7, LPAM-1, LPAM1, Lymphocyte Peyer PatchAdhesion Molecule
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纯化方法
- Purified
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免疫原
- AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref. 1)
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亚型
- IgG2a
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anti-Integrin beta 7 (ITGB7) (AA 1-798) antibody
ITGB7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) (Internal Region) antibodyITGB7 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) (AA 721-806) antibodyITGB7 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) antibodyITGB7 适用: 人, 小鼠 FACS, IP, BR 宿主: 兔 Chimeric FIB27 unconjugated Recombinant Antibody
anti-Integrin beta 7 (ITGB7) antibodyITGB7 适用: 人, 小鼠 FACS, IF, BR 宿主: 兔 Chimeric FIB504 unconjugated Recombinant Antibody
anti-Integrin beta 7 (ITGB7) (AA 1-798) antibodyITGB7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 7 (ITGB7) (AA 401-505) antibodyITGB7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 8D3 unconjugated
anti-Integrin beta 7 (ITGB7) antibodyITGB7 适用: 人, 小鼠 FACS 宿主: 大鼠 Monoclonal FIB504 unconjugated
anti-Integrin beta 7 (ITGB7) (AA 737-765) antibodyITGB7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1-4)Immunohistochemistry on Frozen Sections. (Ref.3)Induction of homotypic cellular aggregation. Blockade of binding to cell adhesion molecules.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Integrin beta 7 (ITGB7)
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别名
- Integrin beta-7
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背景
- The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4)Synonyms: Adhesion Molecule, ITGB7, Integrin beta-P, LPAM-1, LPAM1, Lymphocyte Peyer Patch, M290 IEL antigen
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基因ID
- 16421
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UniProt
- P26011
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途径
- Integrin Complex
抗原
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