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Integrin beta 7 抗体

This anti-Integrin beta 7 antibody is a 大鼠 单克隆 antibody detecting Integrin beta 7 in FACS, IHC (fro) 和 Func. Suitable for 小鼠.
产品编号 ABIN371134
发货至: 中国

Quick Overview for Integrin beta 7 抗体 (ABIN371134)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Integrin beta 7 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

DATK32
  • 特异性

    This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7). It recognises a conformational epitope on the heterodimer.

    产品特性

    Synonyms: Integrin alpha-4/beta-7, Integrin alpha 4, Integrin beta 7, ITGA4, ITGB7, LPAM1, CD49d,VLA-4, Lymphocyte Peyer PatchAdhesion Molecule

    内毒素水平

    Low Endotoxin

    免疫原

    AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref. 1)

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry. (Ref.1-4)Immunohistochemistry on Frozen Sections. (Ref.3)Induction of homotypic cellular aggregation. Blockade of binding to cell adhesion molecules.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing no preservatives.

    储存液

    Without preservative

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted in (aliquots) at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin beta-7

    背景

    The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4)Synonyms: Adhesion Molecule, CD49d, ITGA4, ITGB7, Integrin alpha 4, Integrin alpha-4/beta-7, Integrin beta 7, LPAM1, Lymphocyte Peyer Patch, VLA-4

    基因ID

    16421

    UniProt

    P26011

    途径

    Integrin Complex
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