ENG
适用: 人
WB, IHC, ELISA
宿主: 兔
Polyclonal
unconjugated
应用备注
Flow Cytometry: Identification and enumeration of CD105+ cells. (< / = 1 μg/10^6 cells). Immunohistochemistry on Frozen Sections. Western Blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
0.5 mg/mL
缓冲液
100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
抗原
Endoglin (ENG)
别名
CD105 / Endoglin
背景
CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. (Ref.2) Both mouse and human CD105 exhibit > 70 % sequence homology in their cytoplasmic domains with type III Transforming Growth Factor beta (TGF-beta) receptor. (Ref.3) CD105 has been shown to be one of several receptors for the various isoforms of TGF-beta, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response. (Ref.4)Synonyms: END, ENG, HHT1, ORW, ORW1