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Endoglin 抗体

This anti-Endoglin antibody is a 大鼠 单克隆 antibody detecting Endoglin in WB, FACS 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN371132
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Endoglin 抗体 (ABIN371132)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

MJ7-18
  • 产品特性

    Synonyms: ENG, END, HHT1, ORW, ORW1

    纯化方法

    Purified

    免疫原

    Inflamed mouse skin. (Ref. 1)

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry: Identification and enumeration of CD105+ cells. (< / = 1 μg/10^6 cells). Immunohistochemistry on Frozen Sections. Western Blotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Endoglin (ENG)

    别名

    CD105 / Endoglin

    背景

    CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. (Ref.2) Both mouse and human CD105 exhibit > 70 % sequence homology in their cytoplasmic domains with type III Transforming Growth Factor beta (TGF-beta) receptor. (Ref.3) CD105 has been shown to be one of several receptors for the various isoforms of TGF-beta, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response. (Ref.4)Synonyms: END, ENG, HHT1, ORW, ORW1

    UniProt

    Q63961
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