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Endoglin 抗体

ENG 适用: 小鼠 WB, FACS, IHC (fro) 宿主: 大鼠 Monoclonal MJ7-18 unconjugated
产品编号 ABIN371132
发货至: 中国
  • 抗原 See all Endoglin (ENG) 抗体
    Endoglin (ENG)
    适用
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    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This Endoglin antibody is un-conjugated
    应用范围
    • 136
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    产品特性
    Synonyms: ENG, END, HHT1, ORW, ORW1
    纯化方法
    Purified
    免疫原
    Inflamed mouse skin. (Ref. 1)
    克隆位点
    MJ7-18
    亚型
    IgG2a
    Top Product
    Discover our top product ENG Primary Antibody
  • 应用备注
    Flow Cytometry: Identification and enumeration of CD105+ cells. (< / = 1 μg/10^6 cells). Immunohistochemistry on Frozen Sections. Western Blotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Endoglin (ENG)
    别名
    CD105 / Endoglin (ENG 产品)
    背景
    CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. (Ref.2) Both mouse and human CD105 exhibit > 70 % sequence homology in their cytoplasmic domains with type III Transforming Growth Factor beta (TGF-beta) receptor. (Ref.3) CD105 has been shown to be one of several receptors for the various isoforms of TGF-beta, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response. (Ref.4)Synonyms: END, ENG, HHT1, ORW, ORW1
    UniProt
    Q63961
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