CD80 抗体 (APC)
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北京 101111
Quick Overview for CD80 抗体 (APC) (ABIN371003)
抗原
See all CD80 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises CD80/B7-1 (Mr. 45-47 kDa)
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产品特性
- Synonyms: CD28LG, CD28LG1, LAB7, BB1, Activation B7-1 antigen, B7.1, T-lymphocyte activationantigen CD80, CTLA-4 counter-receptor B7.1
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亚型
- IgG2a
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) (AA 251-321) antibodyCD80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD80 (CD80) antibodyCD80 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD80 (CD80) antibodyCD80 适用: 小鼠, 犬 FACS, IP, IHC (fro) 宿主: 仓鼠 Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 FITC
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PE
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 APC
anti-CD80 (CD80) antibodyCD80 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2A2 unconjugated
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应用备注
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Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.2,7)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.1 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CD80
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别名
- CD80
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背景
- CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours postactivation. (Ref.1-4) The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. (Ref.5,6). This Monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigenpresenting cells. (Ref.2,7).Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
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基因ID
- 12519
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UniProt
- Q00609
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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