CD40 Ligand 抗体
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北京 101111
Quick Overview for CD40 Ligand 抗体 (ABIN370948)
抗原
See all CD40 Ligand (CD40LG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Synonyms: CD40 ligand, CD40-L, CD40LG, TNFSF5, TRAP, GP39, Tumor necrosis factor ligandsuperfamily member 5, TNF-related activation protein, T-cell antigen Gp39
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纯化方法
- Purified
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免疫原
- Activated mouse Th1 clone D1. 6 (Ref. 1)
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亚型
- IgG
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应用备注
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Flow Cytometry. (Ref.1,5)Immunoprecipitation. Functional Assay: In vivo and in vitro blockage of CD154 function. (Ref.1,3,5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CD40 Ligand (CD40LG)
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别名
- CD154 / CD40L
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背景
- CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. (Ref.1-7) It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporinsensitive. (Ref.6)Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5
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UniProt
- P27548
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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