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CD40 Ligand 抗体

This anti-CD40 Ligand antibody is a 仓鼠 单克隆 antibody detecting CD40 Ligand in FACS, IP 和 Func. Suitable for 小鼠.
产品编号 ABIN370948
发货至: 中国

Quick Overview for CD40 Ligand 抗体 (ABIN370948)

抗原

See all CD40 Ligand (CD40LG) 抗体
CD40 Ligand (CD40LG)

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD40 Ligand antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

MR1
  • 产品特性

    Synonyms: CD40 ligand, CD40-L, CD40LG, TNFSF5, TRAP, GP39, Tumor necrosis factor ligandsuperfamily member 5, TNF-related activation protein, T-cell antigen Gp39

    纯化方法

    Purified

    免疫原

    Activated mouse Th1 clone D1. 6 (Ref. 1)

    亚型

    IgG
  • 应用备注

    Flow Cytometry. (Ref.1,5)Immunoprecipitation. Functional Assay: In vivo and in vitro blockage of CD154 function. (Ref.1,3,5)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    CD154 / CD40L

    背景

    CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. (Ref.1-7) It is an important accessory molecule in T cell-B cell costimulatory interactions, and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporinsensitive. (Ref.6)Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

    UniProt

    P27548

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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