PIK3C3 抗体 (AA 700-850)
Quick Overview for PIK3C3 抗体 (AA 700-850) (ABIN363642)
抗原
See all PIK3C3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-850
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特异性
- Reacts with human VPS34
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交叉反应
- 小鼠, 猪
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交叉反应 （详细）
- Cross reacts with proteins from rat, mouse and porcine. The immunogen sequence has 87 % homology with Xenopus protein. Not tested in other species
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纯化方法
- Antigen affinity purified
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免疫原
- Synthetic peptide made to an internal portion of the human protein (within residues 700-850)
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anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 631-885) antibody
PIK3C3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (pSer164) antibodyPIK3C3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (pSer282) antibodyPIK3C3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 14-39) antibodyPIK3C3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB11895 unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 301-400) antibodyPIK3C3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 700-850), (Catalytic Subunit) antibodyPIK3C3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 150-250) antibodyPIK3C3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) antibodyPIK3C3 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 24-53), (N-Term) antibodyPIK3C3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB1695 unconjugated
anti-Phosphoinositide-3-Kinase, Class 3 (PIK3C3) (AA 770-801), (C-Term) antibodyPIK3C3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10857 unconjugated
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/1 000 - ICC/IF: 1/100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, glycerol 50 % , BSA 0.1 %, Sodium azide 0.05 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 6 months
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- PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
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别名
- VPS34
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背景
- VPS34, also known as phosphoinositide-3-kinase p100 subunit or PIK3C3 (phosphoinositide-3-kinase, class III), is a member of the PI3/PI4-kinase family. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. VPS34 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. It exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. The activity of VPS34 is enhanced by manganese and can be regulated by nutrients, suggesting an important role of VPS34 in the regulation of mTOR protein synthesis. VPS34 also forms a complex with Beclin1 that promotes autophagy and tumor supression.
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途径
- AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy
抗原
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