OCT4 抗体 (AA 100-200)
Quick Overview for OCT4 抗体 (AA 100-200) (ABIN363517)
抗原
See all OCT4 (POU5F1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 100-200
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特异性
 - Reacts with Oct-4 protein from human, mouse, rat and primate
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交叉反应
 - 牛, 猪
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交叉反应 (详细)
 - Predicted to cross react with bovine (93 % ), feline (93 %), porcine (93 %).
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纯化方法
 - Purified
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免疫原
 - Synthetic peptide made to an internal portion of the human OCT4 protein sequence (between residues 100-200)
 
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 2 μg/mL - FC: 1:50-1:200 -ICC/IF, 1:50-1:200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 0.85 mg/mL
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缓冲液
 - Tris-glycine, NaCl 150 mM buffer, Sodium azide 0.05 %
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C/-80 °C
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储存方法
 - Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
 
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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别名
 - Octamer-Binding Protein 4 (Oct-4)
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背景
 - Stem cells are crucial ingredients in the progressive restriction of cellular developmental capacity during mammalian embryogenesis. Until recently, only embryonic stem cells (ESC)had been shown to exhibit the potential to differentiate into cells of the all three germ layers. However, adult stem cells (ASC) can regain pluripotency (potential to differentiate into various lineages) if transferred from one stem-cell microenvironment into another.The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.
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UniProt
 - Q01860
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途径
 - Stem Cell Maintenance
 
抗原
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