PARK7/DJ1 抗体 (C-Term)
Quick Overview for PARK7/DJ1 抗体 (C-Term) (ABIN363457)
抗原
See all PARK7/DJ1 (PARK7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-189, C-Term
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特异性
- Reacts with humanand mouse Protein DJ-1
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交叉反应
- 牛, 小鸡
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交叉反应 (详细)
- May cross react with rat, bovine, Zebra fish, Golden hamster and chicken proteins (100 % sequence homology).
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纯化方法
- Antiserum
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免疫原
- Synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1).
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:500 IP1:200 WB1:2 000 -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 6 months
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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别名
- Protein DJ-1
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背景
- Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
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基因ID
- 11315
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
抗原
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