ARNT 抗体 (AA 496-789)
Quick Overview for ARNT 抗体 (AA 496-789) (ABIN363204)
抗原
See all ARNT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 496-789
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特异性
- Reacts with human HIF 1 beta /ARNT
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交叉反应
- 小鼠, 牛, 绵羊, 大鼠
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交叉反应 (详细)
- Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.
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纯化方法
- Purified (protein G)
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免疫原
- Fusion protein containing amino acids 496-789 of human HIF-1 beta
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亚型
- IgG1 kappa
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP1:10-1:500, IHC1:100, IHC-P 1:100, WB 1:500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.4 mg/mL
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缓冲液
- PBS, Sodium azide 0.05 %
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C/-80 °C
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储存方法
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
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别名
- Hypoxia-Inducible Factor 1-beta
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背景
- HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits which are bHLH proteins of PAS (PER, ARNT, SIM) family. HIF-1 beta forms heterodimer with AHR, AHRR, HIF1 alpha and EPAS1/HIF2 alpha as well as with other bHLH proteins and its dimerization is required for efficient DNA binding. Interact with TACC3 and NOCA7.
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基因ID
- 405
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UniProt
- P27540
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
抗原
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