Paxillin 抗体 (AA 86-90)
Quick Overview for Paxillin 抗体 (AA 86-90) (ABIN363106)
抗原
See all Paxillin (PXN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 86-90
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特异性
- The antibody detects endogenous level of total Paxillin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen .
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免疫原
- Peptide sequence around AA 86-90 (P-V-Y-G-S) derived from Human Paxillin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Lipid raft regulates the initial spreading of melanoma A375 cells by modulating ?1 integrin clustering." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1679-89, (2013) (PubMed).
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: "Lipid raft regulates the initial spreading of melanoma A375 cells by modulating ?1 integrin clustering." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1679-89, (2013) (PubMed).
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- Paxillin (PXN)
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别名
- Paxillin
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背景
- Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
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分子量
- 68 kDa
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NCBI登录号
- NP_001074
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UniProt
- P49023
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途径
- MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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