SMAD3 抗体 (AA 206-210)
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Quick Overview for SMAD3 抗体 (AA 206-210) (ABIN363048)
抗原
See all SMAD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 206-210
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特异性
- The antibody detects endogenous level of total Smad3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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免疫原
- Peptide sequence around AA 206-210 (N-L-S-P-N) derived from Human Smad3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
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Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
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别名
- Smad3
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背景
- Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
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分子量
- 52 kDa
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NCBI登录号
- NP_001138
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UniProt
- P84022
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途径
- Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
抗原
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