PKC delta 抗体 (AA 643-647)
Our Local Distributor
北京 101111
Quick Overview for PKC delta 抗体 (AA 643-647) (ABIN363002)
抗原
See all PKC delta (PKCd) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 643-647
-
特异性
- The antibody detects endogenous level of total PKCd protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
-
免疫原
- Peptide sequence around AA 643-647 (R-L-S-Y-S) derived from Human PKCd. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
-
别名
- PKCdelta
-
背景
- This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol. which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
-
分子量
- 78 kDa
-
NCBI登录号
- NP_006245
-
UniProt
- Q05655
-
途径
- Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
抗原
-