The antibody detects endogenous level of total BIM protein.
纯化方法
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
免疫原
Peptide sequence around AA 67-71 (P-A-S-P-G) derived from Human BIM. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS.