alpha Adducin 抗体 (AA 724-728)
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Quick Overview for alpha Adducin 抗体 (AA 724-728) (ABIN362822)
抗原
See all alpha Adducin (ADD1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 724-728
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特异性
- The antibody detects endogenous level of total ADD1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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免疫原
- Peptide sequence around AA 724-728 (T-P-S-F-L) derived from Human ADD1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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anti-Adducin 1 (Alpha) (ADD1) (AA 388-560) antibody
ADD1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (pSer726) antibodyADD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyADD1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyKD Validated ADD1 适用: 人 WB, IF (p), FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (AA 1-193) antibodyADD1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5D4H1 unconjugated
anti-Adducin 1 (Alpha) (ADD1) (AA 1-662) antibodyADD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Adducin 1 (Alpha) (ADD1) antibodyADD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (Ser726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (pSer726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 1 (Alpha) (ADD1) (Ser713), (Ser726) antibodyADD1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
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别名
- ADD1
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背景
- Adducins are a family of cytoskeleton proteins encoded by three genes (a, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. a- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. a- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.
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分子量
- 130 kDa
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NCBI登录号
- NP_001110
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UniProt
- P35611
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途径
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
抗原
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