(2 references)-
- 抗原 See all HDAC5 抗体
- HDAC5 (Histone Deacetylase 5 (HDAC5))
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抗原表位
- AA 496-500
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HDAC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- The antibody detects endogenous level of total HDAC5 protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- 免疫原
- Peptide sequence around AA 496-500 (T-Q-S-S-P) derived from Human HDAC5, 7. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- 亚型
- IgG
- Top Product
- Discover our top product HDAC5 Primary Antibody
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anti-Histone Deacetylase 5 (HDAC5) (C-Term) antibody
HDAC5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (pSer498) antibodyHDAC5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (AA 550-650) antibodyHDAC5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) antibodyHDAC5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (AA 330-429) antibodyHDAC5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G2 unconjugated
anti-Histone Deacetylase 5 (HDAC5) antibodyHDAC5 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (pSer259) antibodyHDAC5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (Internal Region) antibodyHDAC5 适用: 人 WB, IHC, ELISA, FM 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (C-Term) antibodyHDAC5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Deacetylase 5 (HDAC5) (AA 1-100) antibodyHDAC5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS." in: Blood, Vol. 115, Issue 14, pp. 2971-9, (2010) (PubMed).
: "GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 5, pp. 892-8, (2008) (PubMed).
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: "Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS." in: Blood, Vol. 115, Issue 14, pp. 2971-9, (2010) (PubMed).
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- 抗原
- HDAC5 (Histone Deacetylase 5 (HDAC5))
- 别名
- HDAC5 (HDAC5 产品)
- 别名
- HD5 antibody, NY-CO-9 antibody, AI426555 antibody, Hdac4 antibody, mHDA1 antibody, mKIAA0600 antibody, ATHDA5 antibody, HDA5 antibody, MAF19.7 antibody, MAF19_7 antibody, histone deacetylase 5 antibody, histone deacetylase 5 antibody, HDAC5 antibody, Hdac5 antibody, HDA05 antibody, hdac5 antibody
- 背景
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 124 kDa
- NCBI登录号
- NP_001015
- UniProt
- Q9UQL6
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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