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TYK2 抗体 (AA 1052-1056)

This 兔 多克隆 anti-TYK2 antibody specifically detects TYK2 in IHC. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN362700
发货至: 中国
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Quick Overview for TYK2 抗体 (AA 1052-1056) (ABIN362700)

抗原

See all TYK2 抗体
TYK2 (Tyrosine Kinase 2 (TYK2))

适用

  • 85
  • 34
  • 28
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 73
  • 12

克隆类型

  • 73
  • 13
多克隆

标记

  • 39
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TYK2 antibody is un-conjugated

应用范围

  • 67
  • 34
  • 16
  • 15
  • 13
  • 13
  • 10
  • 8
  • 5
  • 4
  • 4
  • 2
Immunohistochemistry (IHC)
  • 抗原表位

    • 17
    • 15
    • 15
    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1052-1056

    特异性

    The antibody detects endogenous level of total TYK2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    免疫原

    Peptide sequence around AA 1052-1056 (H-E-Y-Y-R) derived from Human TYK2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    TYK2 (Tyrosine Kinase 2 (TYK2))

    别名

    TYK2

    背景

    TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin

    分子量

    140 kDa

    NCBI登录号

    NP_003322

    UniProt

    P29597

    途径

    JAK/STAT Signaling, Hepatitis C
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