TYK2 抗体 (AA 1052-1056)
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Quick Overview for TYK2 抗体 (AA 1052-1056) (ABIN362700)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1052-1056
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特异性
- The antibody detects endogenous level of total TYK2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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免疫原
- Peptide sequence around AA 1052-1056 (H-E-Y-Y-R) derived from Human TYK2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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亚型
- IgG
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应用备注
- Immunohistochemistry: 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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别名
- TYK2
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背景
- TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin
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分子量
- 140 kDa
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NCBI登录号
- NP_003322
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UniProt
- P29597
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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