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ICAM1 抗体 (AA 510-514)

This 兔 多克隆 antibody specifically detects ICAM1 in WB. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN362683
发货至: 中国
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Quick Overview for ICAM1 抗体 (AA 510-514) (ABIN362683)

抗原

See all ICAM1 抗体
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ICAM1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 510-514

    特异性

    The antibody detects endogenous level of total ICAM-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    免疫原

    Peptide sequence around AA 510-514 (K-K-Y-R-L) derived from Human ICAM-1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000  

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Wang, Zhang, Yan, Zhao, Zhou, Wang, Lu, Zhang: "Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK." in: Free radical biology & medicine, Vol. 50, Issue 9, pp. 1094-106, (2011) (PubMed).

    Ould-yahoui, Tremblay, Sbai, Ferhat, Bernard, Charrat, Gueye, Lim, Brew, Risso, Dive, Khrestchatisky, Rivera: "A new role for TIMP-1 in modulating neurite outgrowth and morphology of cortical neurons." in: PLoS ONE, Vol. 4, Issue 12, pp. e8289, (2009) (PubMed).

    Sbai, Ould-Yahoui, Ferhat, Gueye, Bernard, Charrat, Mehanna, Risso, Chauvin, Fenouillet, Rivera, Khrestchatisky: "Differential vesicular distribution and trafficking of MMP-2, MMP-9, and their inhibitors in astrocytes." in: Glia, Vol. 58, Issue 3, pp. 344-66, (2009) (PubMed).

  • 抗原

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    别名

    ICAM-1

    背景

    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin a-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

    分子量

    92 kDa

    NCBI登录号

    NP_000192

    UniProt

    P05362

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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