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c-MYC 抗体 (AA 356-360)

There are 2+ publications for this product available. The 兔多克隆 anti-c-MYC antibody is suitable to detect c-MYC in samples from 人, 小鼠和大鼠. It has been validated for WB 和 IHC.

(2 references)

产品编号 ABIN362550

发货至: 中国

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Quick Overview for c-MYC 抗体 (AA 356-360) (ABIN362550)

抗原

See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This c-MYC antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MYC Primary Antibody

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AA 356-360

特异性

The antibody detects endogenous level of total Myc protein.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

免疫原

Peptide sequence around AA 356-360 (R-R-T-H-N) derived from Human Myc. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

亚型

IgG
anti-Myc Proto-Oncogene protein (MYC) (Center) antibody
MYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 360-440) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
MYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 257-439) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Giugliano, Ruff, Braunwald, Murphy, Wiviott, Halperin, Waldo, Ezekowitz, Weitz, Špinar, Ruzyllo, Ruda, Koretsune, Betcher, Shi, Grip, Patel, Patel, Hanyok, Mercuri, Antman: "Edoxaban versus warfarin in patients with atrial fibrillation." in: The New England journal of medicine, Vol. 369, Issue 22, pp. 2093-104, (2013) (PubMed).

Liu, Ma, Lee: "NMDA receptor signaling mediates the expression of protein inhibitor of activated STAT1 (PIAS1) in rat hippocampus." in: Neuropharmacology, Vol. 65, pp. 101-13, (2012) (PubMed).
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

Myc Proto-Oncogene protein

背景

Myc proto-oncogene encodes nuclear DNA-binding phosphoproteins that are involved in the regulation of gene expression and DNA replication during cell growth and differentiation. Myc encodes a protein of 65 kDa which is expressed in almost all normal and transformed cells. The expression correlates with the proliferation state of the cells. Transcription is repressed in quiescent or terminally differentiated cells. Expression of Myc is generally induced after mitogenic stimulation of cells or serum induction. Myc therefore is an important positive regulator of cell growth and proliferation. Myc has been demonstrated also to be a potent inducer of apoptosis when expressed in the absence of serum or growth factors. Apoptosis may serve also as a protective mechanism to prevent tumorigenicity elicited by deregulated Myc expression. Sequences of the Myc oncogene have been highly conserved throughout evolution, from Drosophila to vertebrates

分子量

60 kDa

NCBI登录号

NP_002458

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect