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MAPKAP Kinase 2 抗体 (pThr334)

MAPKAPK2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN362396
发货至: 中国
  • 抗原 See all MAPKAP Kinase 2 (MAPKAPK2) 抗体
    MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
    抗原表位
    • 31
    • 25
    • 19
    • 16
    • 7
    • 7
    • 3
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    pThr334
    适用
    • 102
    • 95
    • 91
    • 21
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 130
    • 3
    • 2
    克隆类型
    • 120
    • 15
    多克隆
    标记
    • 59
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This MAPKAP Kinase 2 antibody is un-conjugated
    应用范围
    • 89
    • 43
    • 40
    • 39
    • 33
    • 24
    • 15
    • 13
    • 9
    • 8
    • 8
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    特异性
    The antibody detects endogenous level of MAPKAPK-2 only when phosphorylated at threonine 334.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    免疫原
    Peptide sequence around phosphorylation site of pThr334 (P-Q-T (p) -P-L) derived from Human MAPKAPK-2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    亚型
    IgG
    Top Product
    Discover our top product MAPKAPK2 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
    别名
    MAPKAPK-2 (MAPKAPK2 产品)
    别名
    mapkapk2 antibody, wu:fb30e10 antibody, wu:fc56c10 antibody, wu:fi03a01 antibody, MGC78852 antibody, MAPKAPK2 antibody, AA960234 antibody, MAPKAP-K2 antibody, MK-2 antibody, MK2 antibody, Rps6kc1 antibody, mitogen-activated protein kinase-activated protein kinase 2a antibody, mitogen-activated protein kinase-activated protein kinase 2 L homeolog antibody, mitogen-activated protein kinase-activated protein kinase 2 antibody, MAP kinase-activated protein kinase 2 antibody, mapkapk2a antibody, mapkapk2.L antibody, MAPKAPK2 antibody, Mapkapk2 antibody
    背景
    MAPKAPK-2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
    分子量
    49 kDa
    NCBI登录号
    NP_004750
    UniProt
    P49137
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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