PKC delta 抗体 (pSer645)
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北京 101111
Quick Overview for PKC delta 抗体 (pSer645) (ABIN362383)
抗原
See all PKC delta (PKCd) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer645
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特异性
- The antibody detects endogenous level of PKCd only when phosphorylated at serine 645.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- Peptide sequence around phosphorylation site of pSer645 (R-L-S (p) -Y-S) derived from Human PKCd. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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亚型
- IgG
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anti-Protein Kinase C, delta (PKCd) (AA 477-676) antibody
PKCd 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) antibodyKD Validated PKCd 适用: 小鼠 WB, IF (p), FACS 宿主: 兔 Monoclonal 24GB4485 unconjugated Recombinant Antibody
anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibodyPKCd 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6A2 unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibodyPKCd 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Protein Kinase C, delta (PKCd) (pTyr313) antibodyPKCd 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (C-Term) antibodyPKCd 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) antibodyKD Validated PKCd 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2410 unconjugated Recombinant Antibody
anti-Protein Kinase C, delta (PKCd) (pSer645) antibodyPKCd 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (pTyr64) antibodyPKCd 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 1-676) antibodyPKCd 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Protein kinase C mRNA and protein expressions in hypobaric hypoxia-induced cardiac hypertrophy in rats." in: Acta physiologica (Oxford, England), Vol. 198, Issue 4, pp. 431-40, (2010) (PubMed).
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- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
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别名
- PKCdelta
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背景
- This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
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分子量
- 78 kDa
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NCBI登录号
- NP_006245
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UniProt
- Q05655
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途径
- Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
抗原
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