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Cortactin 抗体 (pTyr466)

The 兔多克隆 anti-Cortactin antibody is suitable to detect Cortactin in samples from 人和小鼠. It has been validated for WB.

产品编号 ABIN362345

发货至: 中国

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Quick Overview for Cortactin 抗体 (pTyr466) (ABIN362345)

抗原

See all Cortactin (CTTN) 抗体

Cortactin (CTTN)

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This Cortactin antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CTTN Primary Antibody

抗原表位
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pTyr466

特异性

The antibody detects endogenous level of Cortactin only when phosphorylated at tyrosine 466.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

Peptide sequence around phosphorylation site of pTyr466 (P-V-Y (p) -E-T) derived from Human CORTACTIN. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

亚型

IgG
anti-Cortactin (CTTN) (N-Term) antibody
KO Validated CTTN 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) antibody
CTTN 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Cortactin (CTTN) (AA 214-513) antibody
CTTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (AA 1-105) antibody
CTTN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (pTyr466) antibody
CTTN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (AA 341-450) antibody
CTTN 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B5 unconjugated

anti-Cortactin (CTTN) antibody
CTTN 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated

anti-Cortactin (CTTN) antibody
KD Validated CTTN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2335 unconjugated Recombinant Antibody

anti-Cortactin (CTTN) (AA 1-509) antibody
CTTN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (AA 1-509) antibody
CTTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: 1:500-1:1000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原

Cortactin (CTTN)

别名

Cortactin

背景

Cortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene.

分子量

85 kDa

NCBI登录号

NP_005222

UniProt

Q14247

途径

MAPK Pathway