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VAV1 抗体 (pTyr174)

This 兔 多克隆 antibody specifically detects VAV1 in WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.It has been mentioned in 1 publication
产品编号 ABIN362131
发货至: 中国
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Quick Overview for VAV1 抗体 (pTyr174) (ABIN362131)

抗原

See all VAV1 抗体
VAV1 (Vav 1 Oncogene (VAV1))

适用

  • 73
  • 43
  • 28
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
人, 大鼠, 小鼠

宿主

  • 68
  • 7

克隆类型

  • 68
  • 7
多克隆

标记

  • 56
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This VAV1 antibody is un-conjugated

应用范围

  • 54
  • 37
  • 20
  • 11
  • 6
  • 6
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 13
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pTyr174

    特异性

    The antibody detects endogenous level of Vav only when phosphorylated at tyrosine 174.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

    免疫原

    Peptide sequence around phosphorylation site of pTyr174 (E-I-Y (p) -E-D) derived from Human Vav. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    亚型

    IgG
  • 应用备注

    Western blotting: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Sekine, Ikeda, Tsuji, Yamamoto, Muromoto, Nanbo, Oritani, Yoshimura, Matsuda: "Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 12, pp. 7966-74, (2009) (PubMed).

  • 抗原

    VAV1 (Vav 1 Oncogene (VAV1))

    别名

    Vav

    背景

    Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation

    分子量

    95 kDa

    NCBI登录号

    NP_005419

    UniProt

    P15498

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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