STAT5A 抗体 (pTyr694)
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Quick Overview for STAT5A 抗体 (pTyr694) (ABIN361966)
抗原
See all STAT5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr694
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特异性
- The antibody detects endogenous level of STAT5A only when phosphorylated at tyrosine 694.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- Peptide sequence around phosphorylation site of pTyr694 (D-G-Y (p) -V-K) derived from Human STAT5A. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
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亚型
- IgG
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应用备注
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "Characterization of the rat oncostatin M receptor complex which resembles the human, but differs from the murine cytokine receptor." in: PLoS ONE, Vol. 7, Issue 8, pp. e43155, (2012) (PubMed).
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- STAT5A (Signal Transducer and Activator of Transcription 5A (STAT5A))
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别名
- STAT5A
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背景
- Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.
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分子量
- 90 kDa
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NCBI登录号
- NP_003143
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UniProt
- P42229
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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