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c-MYC 抗体 (pThr358)

The 兔多克隆 anti-c-MYC antibody (ABIN361942) specifically detects c-MYC in WB, IHC 和 IF. The antibody is reactive with 人, 小鼠和大鼠 samples.

产品编号 ABIN361942

发货至: 中国

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Quick Overview for c-MYC 抗体 (pThr358) (ABIN361942)

抗原

See all c-MYC (MYC) 抗体

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This c-MYC antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product MYC Primary Antibody

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pThr358

特异性

The antibody detects endogenous level of Myc only when phosphorylated at threonine 358.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

Peptide sequence around phosphorylation site of pThr358 (R-R-T (p) -H-N) derived from Human Myc. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

亚型

IgG
anti-Myc Proto-Oncogene protein (MYC) (Center) antibody
MYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 360-440) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myc Proto-Oncogene protein (MYC) antibody
MYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated

anti-Myc Proto-Oncogene protein (MYC) (AA 257-439) antibody
MYC 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C/-20 °C

储存方法

Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
抗原

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

别名

Myc Proto-Oncogene protein

背景

Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.

分子量

60 kDa

NCBI登录号

NP_002458

UniProt

P01106

途径

p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect