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PLK1 抗体 (pSer482, pSer486, pSer490)
PLK1
适用: 非洲爪蟾
WB
宿主: 兔
Polyclonal
unconjugated
PLK1抗体详情
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抗原
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PLK1
(Polo-Like Kinase 1 (PLK1))
抗原表位
All epitopes for PLK1 抗体
pSer482, pSer486, pSer490
适用
All reactivities for PLK1 抗体
非洲爪蟾
宿主
All hosts for PLK1 抗体
兔
克隆类型
All clonalities for PLK1 抗体
多克隆
标记
All conjugates for PLK1 抗体
This PLK1 antibody is un-conjugated
应用范围
All applications for PLK1 抗体
Western Blotting (WB)
特异性
Specific for the ~120k PLKK protein phosphorylated at Ser482,486,490.
交叉反应
非洲爪蟾
预测反应
rat, mouse human, zebra fish
纯化方法
Antigen Affinity Purified from Pooled Serum
免疫原
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser482/486/490 conjugated to KLH
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Alternatives
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使用细节
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应用备注
Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
储存条件
-20 °C
PLK1目标详情
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抗原
PLK1
(Polo-Like Kinase 1 (PLK1))
别名
PLK1 (PLK1 产品 )
别名
PLK antibody, STPK13 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, stpk13 antibody, Plk antibody, cb525 antibody, cb636 antibody, ik:tdsubc_2d1 antibody, wu:fb37g11 antibody, wu:fb76g03 antibody, xx:tdsubc_2d1 antibody, polo like kinase 1 antibody, polo like kinase 1 S homeolog antibody, polo-like kinase 1 antibody, polo-like kinase 1 (Drosophila) antibody, Serine/threonine-protein kinase plk-1 antibody, PLK1 antibody, plk1.S antibody, plk1 antibody, Plk1 antibody, plk-1 antibody
背景
Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.
分子量
'120 kDa
基因ID
380481
UniProt
P70032
途径
Cell Division Cycle , M Phase
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原发性抗体
PLK1 抗体
anti-PLK1 抗体 (pSer482, pSer486, pSer490) (ABIN361516)