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PLK1 抗体 (pSer482, pSer486, pSer490)

PLK1 适用: 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN361516
发货至: 中国
  • 抗原 See all PLK1 抗体
    PLK1 (Polo-Like Kinase 1 (PLK1))
    抗原表位
    • 18
    • 17
    • 15
    • 12
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer482, pSer486, pSer490
    适用
    • 124
    • 48
    • 43
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    非洲爪蟾
    宿主
    • 102
    • 20
    • 2
    • 1
    克隆类型
    • 104
    • 21
    多克隆
    标记
    • 74
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This PLK1 antibody is un-conjugated
    应用范围
    • 100
    • 47
    • 31
    • 28
    • 27
    • 19
    • 18
    • 15
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Specific for the ~120k PLKK protein phosphorylated at Ser482,486,490.
    交叉反应
    非洲爪蟾
    预测反应
    rat, mouse human, zebra fish
    纯化方法
    Antigen Affinity Purified from Pooled Serum
    免疫原
    Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser482/486/490 conjugated to KLH
    Top Product
    Discover our top product PLK1 Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    储存条件
    -20 °C
  • 抗原
    PLK1 (Polo-Like Kinase 1 (PLK1))
    别名
    PLK1 (PLK1 产品)
    别名
    PLK antibody, STPK13 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, stpk13 antibody, Plk antibody, cb525 antibody, cb636 antibody, ik:tdsubc_2d1 antibody, wu:fb37g11 antibody, wu:fb76g03 antibody, xx:tdsubc_2d1 antibody, polo like kinase 1 antibody, polo like kinase 1 S homeolog antibody, polo-like kinase 1 antibody, polo-like kinase 1 (Drosophila) antibody, Serine/threonine-protein kinase plk-1 antibody, PLK1 antibody, plk1.S antibody, plk1 antibody, Plk1 antibody, plk-1 antibody
    背景
    Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.
    分子量
    '120 kDa
    基因ID
    380481
    UniProt
    P70032
    途径
    Cell Division Cycle, M Phase
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