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PLK1 抗体 (pSer482, pSer486, pSer490)

This anti-PLK1 antibody is a 兔多克隆 antibody detecting PLK1 in WB. Suitable for 非洲爪蟾.

Western blot of rat hippocampal membrane lysate showing specific immunolabeling of the ~120 kDa Polo-Like Kinase Kinase phosphorylated at Ser482,486,490 in the first lane (-). (PLK1 抗体 (pSer482, pSer486, pSer490))

1 image

产品编号 ABIN361516

发货至: 中国

Quick Overview for PLK1 抗体 (pSer482, pSer486, pSer490) (ABIN361516)

抗原

See all PLK1 抗体

PLK1 (Polo-Like Kinase 1 (PLK1))

适用

124
46
39
14
7
7
6
5
5
3
3
3
1
1
1
1

非洲爪蟾

宿主

兔

克隆类型

多克隆

标记

77
6
5
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1

This PLK1 antibody is un-conjugated

应用范围

110
49
33
28
27
26
19
19
7
5
4
4
3
2
2
1
1

Western Blotting (WB)

Discover our top product PLK1 Primary Antibody

抗原表位
22

18

15

12

8

5

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer482, pSer486, pSer490

特异性

Specific for the ~120k PLKK protein phosphorylated at Ser482,486,490.

交叉反应

非洲爪蟾

预测反应

rat, mouse human, zebra fish

纯化方法

Antigen Affinity Purified from Pooled Serum

免疫原

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser482/486/490 conjugated to KLH
anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3C11 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibody
PLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 1-603) antibody
PLK1 适用: 人 WB, ELISA, IF, IP, PLA 宿主: 小鼠 Monoclonal 2G12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 5C1 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人, 犬 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 6C6 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 1D4 unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人, 犬, 猴 WB, IF, IP, FACS 宿主: 小鼠 Monoclonal 8C12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 201-300) antibody
PLK1 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Polo-Like Kinase 1 (PLK1) antibody
PLK1 适用: 人 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 3F12 unconjugated

anti-Polo-Like Kinase 1 (PLK1) (AA 331-508) antibody
PLK1 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 1D1 unconjugated

应用备注

Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

限制

仅限研究用
状态

Liquid

缓冲液

100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

储存条件

-20 °C
抗原

PLK1 (Polo-Like Kinase 1 (PLK1))

别名

PLK1

背景

Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting complex/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work (Erikson, et al., 2004) has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.

分子量

'120 kDa

基因ID

380481

UniProt

P70032

途径

Cell Division Cycle, M Phase

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