IFNAR1 抗体 (pSer535, pSer539)
(2 references)Quick Overview for IFNAR1 抗体 (pSer535, pSer539) (ABIN361505)
抗原
See all IFNAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer535, pSer539
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特异性
- Specific for IFNAR1 protein phosphorylated at Ser535,539. Note: the molecular weight of the IFNAR1 varies with cell line (different levels of glycosylation) in 293 and HeLa Cells, the mature form is ~110 kDa - 130 kDa.
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交叉反应
- 人
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预测反应
- bovine, canine, mouse, non-human primate, rat, sheep
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产品特性
- Our Interferon-α Receptor, Type I, Subunit I (Ser535,539) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Interferon-α Receptor, Type I, Subunit I (Ser535,539) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
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纯化方法
- Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.
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免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser535/539 of human interferon-alpha, conjugated to keyhole limpet hemocyanin (KLH).
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亚型
- IgG
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anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 470-557) antibody
IFNAR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 162-188) antibodyIFNAR1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21945 unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (pSer535), (pSer538) antibodyIFNAR1 适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) antibodyIFNAR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) antibodyIFNAR1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (pSer535), (pSer539) antibodyIFNAR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-127) antibodyIFNAR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (pSer535), (Ser539) antibodyIFNAR1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 351-450) antibodyIFNAR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 162-188) antibodyIFNAR1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
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有效期
- 12 months
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: "Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor." in: The Journal of biological chemistry, Vol. 285, Issue 4, pp. 2318-25, (2010) (PubMed).
: "Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46614-20, (2004) (PubMed).
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: "Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor." in: The Journal of biological chemistry, Vol. 285, Issue 4, pp. 2318-25, (2010) (PubMed).
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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别名
- IFNAR1
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背景
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Synonyms: Alpha-Type Antiviral Protein, AVP, Beta-Type Antiviral Protein, CRF2-1, Cytokine Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, IFN-Alpha/Beta Receptor 1, IFNBR, IFN-Alpha-REC, IFNAR, IFN-R-1, IFRC, Interferon Alpha/Beta Receptor 1, Interferon-Alpha/Beta Receptor Alpha Chain, Interferon Alpha And Beta Receptor Subunit 1, Interferon (Alpha, Beta And Omega) Receptor 1, Interferon-Beta Receptor 1, Interferon Receptor 1, Type I Interferon Receptor 1
Description Logic: Our Interferon-α Receptor, Type I, Subunit I (Ser535,539) rabbit polyclonal phosphospecific primary antibody is produced . It detects Interferon-α Receptor, Type I, Subunit I (Ser535,539) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.
Gene Name Alternatives: IFNAR1
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分子量
- 110 kDa-130 kDa
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基因ID
- 3654
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UniProt
- P17181
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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