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Retinoic Acid Receptor beta 抗体 (N-Term)

This anti-Retinoic Acid Receptor beta antibody is a 小鼠 单克隆 antibody detecting Retinoic Acid Receptor beta in WB. Suitable for 人.
产品编号 ABIN361388
发货至: 中国

Quick Overview for Retinoic Acid Receptor beta 抗体 (N-Term) (ABIN361388)

抗原

See all Retinoic Acid Receptor beta (RARB) 抗体
Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

适用

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宿主

  • 65
  • 10
小鼠

克隆类型

  • 65
  • 10
单克隆

标记

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This Retinoic Acid Receptor beta antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

336
  • 抗原表位

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    N-Term

    特异性

    Specific for the ~48k RAR-( isotype.

    交叉反应

    人, 大鼠

    预测反应

    canine, guinea pig, mouse, non-human primate

    纯化方法

    Protein G purified culture supernatant

    免疫原

    Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH

    亚型

    IgG1
  • 应用备注

    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

    储存条件

    -20 °C
  • 抗原

    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

    别名

    RARB

    背景

    Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRa, ß and () preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti- Retinoic Acid Receptor, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RAR-ß isotype.

    分子量

    '48 kDa

    基因ID

    5915

    UniProt

    P10826

    途径

    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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