NEFL 抗体
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北京 101111
Quick Overview for NEFL 抗体 (ABIN361353)
抗原
See all NEFL 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections.
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交叉反应
- 小鸡, 牛, 人, 小鼠, 大鼠
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纯化方法
- Total IgY fraction
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免疫原
- Preparation of bovine spinal cord NF-L
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应用备注
- Recommended Dilution: WB: 1:10,000 IF: 1:5,000 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- total IgY fraction in PBS + 10 mM Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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别名
- NEFL
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背景
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2). Anti-Neurofilament L Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.
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分子量
- '68 kDa
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基因ID
- 4747
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UniProt
- P02548
抗原
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