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NEFH 抗体

NEFH 适用: Cow WB, IF 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN361351
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    适用
    • 108
    • 81
    • 63
    • 48
    • 28
    • 27
    • 12
    • 12
    • 9
    • 9
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    • 7
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    • 5
    • 3
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    • 2
    • 1
    Cow
    宿主
    • 67
    • 55
    • 8
    小鸡
    克隆类型
    • 82
    • 48
    多克隆
    标记
    • 87
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This NEFH antibody is un-conjugated
    应用范围
    • 88
    • 42
    • 37
    • 29
    • 26
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    • 22
    • 15
    • 14
    • 13
    • 13
    • 9
    • 5
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Specific for the ~200k Neurofilament H protein.
    交叉反应
    小鸡, 哺乳动物
    纯化方法
    Total IgY fraction
    免疫原
    Purified bovine NF-H
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:50,000 IF: 1:25,000 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    total IgY fraction in PBS + 10 mM Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Malara, Lutz, Incearap, Bauer, Cursano, Volbracht, Lerner, Pandey, Delling, Ioannidis, Arévalo, von Bernhardi, Schön, Bockmann, Dimou, Boeckers: "SHANK3 deficiency leads to myelin defects in the central and peripheral nervous system." in: Cellular and molecular life sciences : CMLS, Vol. 79, Issue 7, pp. 371, (2022) (PubMed).

  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    NEFH (NEFH 产品)
    别名
    NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
    背景
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3). Anti-Neurofilament H Left: Western blot of rat cortex lysate showing specific immunolableing of the ~200k NF-H protein. Right: Immunofluorescence of rat cortical neurons and glia showing NF-H staining (red).
    分子量
    '200 kDa
    基因ID
    4744
    UniProt
    P12036
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