PLAUR 抗体
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北京 101111
Quick Overview for PLAUR 抗体 (ABIN360948)
抗原
See all PLAUR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects uPAR.
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纯化方法
- Protein A/G Affinity Chromatography
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免疫原
- Purified Mouse Recombinant uPAR
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亚型
- IgG2
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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缓冲液
- PBS, None
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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别名
- CD87 / uPAR
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背景
- UPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.Synonyms: MO3, Monocyte activation antigen Mo3, PLAUR, U-PAR, Urokinase plasminogen activator surface receptor
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基因ID
- 18793
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NCBI登录号
- NP_035243
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UniProt
- P35456
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途径
- Inositol Metabolic Process
抗原
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