TREM1 抗体 (Extracellular Domain)
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Quick Overview for TREM1 抗体 (Extracellular Domain) (ABIN360943)
抗原
See all TREM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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纯化方法
- Affinity Chromatography on Protein A/G.
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免疫原
- Purified Mouse Recombinant TREM-1 extracellular domain.
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亚型
- IgG2
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应用备注
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Western blotting: 1/500-1000. Immunohistochemistry on Frozen Sections: 1/50-100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 0.5 mg/mL.
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缓冲液
- PBS without preservatives or stabilizers
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- The lyophilized IgG is stable at 2-8 °C for one month and for one year when kept at -20 °C. Reconstituted antibody can also be aliquotted and stored at -20 °C to -70 °C for 6 months without detectable loss of activity.
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有效期
- 12 months
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- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
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别名
- TREM1
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背景
- TREM1 is also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. TREM1 is a Type I membrane protein that contains an immunoglobulin-like V-type domain. An alternatively spliced protein variant may be secreted. TREM1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes), TREM1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock.Synonyms: Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1
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分子量
- 26 kDa
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NCBI登录号
- NM_021406
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UniProt
- Q9JKE2
抗原
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