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TREM1 抗体 (Extracellular Domain)

This anti-TREM1 antibody is a 大鼠 单克隆 antibody detecting TREM1 in WB 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN360943
发货至: 中国

Quick Overview for TREM1 抗体 (Extracellular Domain) (ABIN360943)

抗原

See all TREM1 抗体
TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

适用

  • 74
  • 53
  • 43
  • 16
  • 7
  • 3
  • 1
  • 1
小鼠

宿主

  • 88
  • 20
  • 7
  • 1
大鼠

克隆类型

  • 89
  • 25
  • 1
单克隆

标记

  • 58
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This TREM1 antibody is un-conjugated

应用范围

  • 91
  • 53
  • 32
  • 26
  • 25
  • 16
  • 15
  • 13
  • 8
  • 8
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

3C66
  • 抗原表位

    • 16
    • 16
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain

    纯化方法

    Affinity Chromatography on Protein A/G.

    免疫原

    Purified Mouse Recombinant TREM-1 extracellular domain.

    亚型

    IgG2
  • 应用备注

    Western blotting: 1/500-1000. Immunohistochemistry on Frozen Sections: 1/50-100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 200 μL sterile PBS and the final concentration is 0.5 mg/mL.

    缓冲液

    PBS without preservatives or stabilizers

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized IgG is stable at 2-8 °C for one month and for one year when kept at -20 °C. Reconstituted antibody can also be aliquotted and stored at -20 °C to -70 °C for 6 months without detectable loss of activity.

    有效期

    12 months
  • 抗原

    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

    别名

    TREM1

    背景

    TREM1 is also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. TREM1 is a Type I membrane protein that contains an immunoglobulin-like V-type domain. An alternatively spliced protein variant may be secreted. TREM1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes), TREM1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock.Synonyms: Triggering receptor expressed on monocytes 1, Triggering receptor expressed on myeloid cells 1

    分子量

    26 kDa

    NCBI登录号

    NM_021406

    UniProt

    Q9JKE2
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