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JAM2 抗体 (Extracellular Domain)

This anti-JAM2 antibody is a 大鼠 单克隆 antibody detecting JAM2 in WB. Suitable for 小鼠.
产品编号 ABIN360922
发货至: 中国

Quick Overview for JAM2 抗体 (Extracellular Domain) (ABIN360922)

抗原

See all JAM2 抗体
JAM2 (Junctional Adhesion Molecule 2 (JAM2))

适用

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  • 2
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小鼠

宿主

  • 35
  • 6
  • 1
大鼠

克隆类型

  • 36
  • 6
单克隆

标记

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  • 1
This JAM2 antibody is un-conjugated

应用范围

  • 36
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  • 21
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  • 4
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  • 1
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Western Blotting (WB)

克隆位点

2K15
  • 抗原表位

    • 12
    • 7
    • 5
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    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    Extracellular Domain

    特异性

    This antibody detects Mouse JAM-B in Western blotting. Other species not tested.

    纯化方法

    Purified

    免疫原

    Recombinant protein of JAM-A extracellular domain

    亚型

    IgG1
  • 应用备注

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.

    缓冲液

    0.2 μm filtered PBS, None

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    JAM2 (Junctional Adhesion Molecule 2 (JAM2))

    别名

    CD322 / JAM2

    背景

    Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1. Junctional adhesion molecule 2 (JAM2), also know as JAMB, is a member of the newly reported glycoprotein family of adhesion molecules found at intercellular junctions of endothelial cells and lymphocytes (human). In adult murine tissue JAM2 expression is restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.Synonyms: C21orf43, JAM-B, Junctional adhesion molecule 2, Junctional adhesion molecule B, VEJAM, Vascular endothelial junction-associated molecule

    基因ID

    67374

    NCBI登录号

    NP_076333

    UniProt

    Q9JI59
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