Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
溶解方式
Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.
缓冲液
0.2 μm filtered PBS, None
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
JAM2
(Junctional Adhesion Molecule 2 (JAM2))
别名
CD322 / JAM2
背景
Members of the junctional adhesion molecule (JAM) family are type I transmembrane glycoproteins of the immunoglobulin (Ig) superfamily that are localized in the tight junctions between endothelial or epithelial cells and appear to be involved in leukocyte transmigration. JAM-A, also known as platelet adhesion molecule 1 (PAM-1) and platelet F11 receptor, contains two V-type Ig-like domains, forms homodimers, and interacts with LFA-1. JAM-B (vasculoendothelial or VE-JAM) and JAM-C each contain two Ig domains (one V-type and one C2-type), a cytoplasmic PDZ-binding motif and a PKC phosphorylation site. JAM-C interacts with MAC-1 and facilitates JAM-B interaction with integrin alpha 4 beta 1. Junctional adhesion molecule 2 (JAM2), also know as JAMB, is a member of the newly reported glycoprotein family of adhesion molecules found at intercellular junctions of endothelial cells and lymphocytes (human). In adult murine tissue JAM2 expression is restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney.Synonyms: C21orf43, JAM-B, Junctional adhesion molecule 2, Junctional adhesion molecule B, VEJAM, Vascular endothelial junction-associated molecule