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IL21 Receptor 抗体 (Extracellular Domain)

This anti-IL21 Receptor antibody is a 大鼠 单克隆 antibody detecting IL21 Receptor in WB. Suitable for 小鼠.
产品编号 ABIN360918
发货至: 中国

Quick Overview for IL21 Receptor 抗体 (Extracellular Domain) (ABIN360918)

抗原

See all IL21 Receptor (IL21R) 抗体
IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

适用

  • 36
  • 30
  • 7
  • 1
小鼠

宿主

  • 47
  • 6
  • 2
  • 1
  • 1
大鼠

克隆类型

  • 46
  • 8
  • 2
单克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This IL21 Receptor antibody is un-conjugated

应用范围

  • 38
  • 21
  • 14
  • 13
  • 13
  • 9
  • 6
  • 5
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)

克隆位点

7F27
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    Extracellular Domain

    特异性

    This antibody detects IL-21R.

    纯化方法

    Protein A/G affinity chromatography

    免疫原

    Recombinant protein of IL-21R extracellular domain.

    亚型

    IgG1
  • 应用备注

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

    别名

    Interleukin-21 Receptor / IL21R

    背景

    IL21 Receptor is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.Synonyms: IL-21R, IL21 receptor, NILR, Novel interleukin receptor

    基因ID

    50615

    NCBI登录号

    NP_068570

    UniProt

    Q9HBE5

    途径

    JAK/STAT Signaling
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