IL21 Receptor 抗体 (Extracellular Domain)
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Quick Overview for IL21 Receptor 抗体 (Extracellular Domain) (ABIN360918)
抗原
See all IL21 Receptor (IL21R) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody detects IL-21R.
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纯化方法
- Protein A/G affinity chromatography
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免疫原
- Recombinant protein of IL-21R extracellular domain.
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亚型
- IgG1
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
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别名
- Interleukin-21 Receptor / IL21R
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背景
- IL21 Receptor is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.Synonyms: IL-21R, IL21 receptor, NILR, Novel interleukin receptor
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基因ID
- 50615
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NCBI登录号
- NP_068570
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UniProt
- Q9HBE5
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途径
- JAK/STAT Signaling
抗原
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