IGFBP6 抗体
Our Local Distributor
北京 101111
Quick Overview for IGFBP6 抗体 (ABIN360903)
抗原
See all IGFBP6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Protein A/G affinity chromatography
-
免疫原
- Recombinant protein of IGF-BP6
-
亚型
- IgG2
-
-
-
-
应用备注
-
Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
-
别名
- IGFBP6
-
背景
- IGFBP6 (IGF binding protein 6) is a member of the IGFBP family that regulates the actions of IGFs. It acts extracellularly in an autocrine/paracrine manner. IGFBP6 binds preferentially to IGF-II. IGFBP6 has been shown to inhibit the growth of tumour cells and to promote apotosis. IGFBP6 has been shown to be imported into the nuclei of rhabdomyosarcoma and HEK-293 cells. This is mediated by a NLS sequence that bears limited homology to those found in IGFBP-3 and -5. Deletion of the NLS segment abolishes the pro-apoptotic effect of IGFBP6.Synonyms: IBP-6, IBP6, IGF-binding protein 6, IGFBP-6, Insulin-like growth factor-binding protein 6
-
基因ID
- 10090
-
UniProt
- P47880
-
途径
- WNT signaling, Myometrial Relaxation and Contraction
抗原
-