GAS6 抗体
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北京 101111
Quick Overview for GAS6 抗体 (ABIN360889)
抗原
See all GAS6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The monoclonal antibody detects Gas6.
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纯化方法
- Protein A/G Affinity Chromatography
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免疫原
- Purified Mouse Recombinant Gas6
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亚型
- IgG2
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anti-Growth Arrest-Specific 6 (GAS6) (AA 483-646) antibody
GAS6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 551-650) antibodyGAS6 适用: 人, 小鼠, Pig WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 136-311) antibodyGAS6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 503-664) antibodyGAS6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 59-221) antibodyGAS6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 100-300) antibodyGAS6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 1-678) antibodyGAS6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 488-660) antibodyGAS6 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 100-312) antibodyGAS6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 70-217) antibodyGAS6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
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缓冲液
- 0.2 μm filtered PBS without preservatives or stabilizers
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GAS6 (Growth Arrest-Specific 6 (GAS6))
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别名
- GAS6 / AXLLG
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背景
- Gas6 (Growth Arrest Specific 6) is one of six structurally unrelated proteins that are secreted by a wide variety of cell types in response to growth arrest. Gas6 and the structurally related Protein S are vitamin K-dependent and have an extensively gamma-carboxylated N-terminal Gla domain, four EGF like repeats, and a C-terminal region with homology to steroid hormone binding globulin (SHBG). Human Gas6 is a 75 kDa protein that shares 77 % -79 % aa sequence identity with mouse and rat Gas6. Alternate splicing generates isoforms that lack the Gla domain and/or the spacer between the EGF-like and SHBG regions. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer. Human Gas6 interacts with both mouse and rat orthologs of these receptors. The full length isoform may be cleaved, resulting in release of the free SHBG region which can independently activate Axl. Shed soluble forms of Axl and Mer bind Gas6 and function as decoy receptors.Synonyms: AXL receptor tyrosine kinase ligand, GAS-6, Growth arrest-specific protein 6
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基因ID
- 2621
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NCBI登录号
- NP_000811
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UniProt
- Q14393
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途径
- RTK signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
抗原
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