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LGALS1/Galectin 1 抗体

This anti-LGALS1/Galectin 1 antibody is a 大鼠 单克隆 antibody detecting LGALS1/Galectin 1 in WB 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN360886
发货至: 中国

Quick Overview for LGALS1/Galectin 1 抗体 (ABIN360886)

抗原

See all LGALS1/Galectin 1 (LGALS1) 抗体
LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This LGALS1/Galectin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

9J26
  • 特异性

    This antibody detects Mouse Galectin-1. Other species not tested.

    纯化方法

    Protein A/G Affinity Chromatography

    过滤

    0.2 μm filtered

    免疫原

    Purified Recombinant Mouse Galectin-1 Remarks: Mouse myeloma fused with spleen cells from a rat

    亚型

    IgG2
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry on frozen sections: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

    缓冲液

    0.2 μm filtered solution in PBS without preservatives or stabilizers

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

    别名

    Galectin-1

    背景

    The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin 1 may act as an autocrine negative growth factor that regulates cell proliferation. It also may regulate cell apoptosis and cell differentiation. It binds beta-galactoside, CD45, CD3 and CD4. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities. Galectin 1 inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. It is found in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney, placenta and hematopoietic cells.Synonyms: 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Galectin1, HBL, HPL, LGALS1, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, MAPK-activating protein PM12, S-Lac lectin 1

    基因ID

    16852

    NCBI登录号

    NP_032521

    UniProt

    P16045

    途径

    Carbohydrate Homeostasis
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