Decorin 抗体
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北京 101111
Quick Overview for Decorin 抗体 (ABIN360879)
抗原
See all Decorin (DCN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects Mouse Decorin in Western blotting.
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纯化方法
- Protein A/G affinity chromatography
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免疫原
- Recombinant Decorin
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亚型
- IgG2
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anti-Decorin (DCN) (AA 31-359) antibody
DCN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 1-359) antibodyDCN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H4-1F4 unconjugated
anti-Decorin (DCN) (AA 263-324) antibodyDCN 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5E8E7 unconjugated
anti-Decorin (DCN) (AA 122-150) antibodyDCN 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19595 unconjugated
anti-Decorin (DCN) (Internal Region) antibodyDCN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) antibodyDCN 适用: 人 WB, IHC (p), IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 31-359) antibodyDCN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 343-359), (C-Term) antibodyDCN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) antibodyDCN 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Decorin (DCN) (AA 31-359) antibodyDCN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 0.2 mL sterile PBS and the final concentration is 0.5 mg/mL.
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缓冲液
- 0.2 μm filtered PBS solution
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Decorin (DCN)
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别名
- Decorin
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背景
- Secreted chondroitin/dermatan sulfate proteoglycan belonging to the class I small leucine-rich proteoglycan family (SLRP). All SLRP family members are characterized by the Nterminal and C terminal cysteine rich regions, which flank the central region containing 1012 tandem leucinerich repeats. In mouse Decorin, the glycosaminoglycan chain is Olinked to Ser34 in the Nterminal disulfide bridged loop. Decorin binds to fibronectin, TGFβ, type I and type II collagen. The binding of Decorin to these molecules is mediated via the core protein. Decorin plays a role in maintaining collagen fibrillogenesis. Depending on the cell context, Decorin can either block or augment the bioactivity of TGFβ Decorin induces growth suppression by activation of a signaling pathway that culminates in the blockade of the cell cycle machinery. Decorin can also induce fibroblast cytoskeletal and signalling changes that results in an increased cell migration (1 2).Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B
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基因ID
- 13179
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NCBI登录号
- NP_001177380
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UniProt
- P28654
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途径
- Glycosaminoglycan Metabolic Process
抗原
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