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VEGFC 抗体

VEGFC 适用: 人, 大鼠 WB, EIA 宿主: 小鼠 Monoclonal 107F10 unconjugated
产品编号 ABIN360868
发货至: 中国
  • 抗原 See all VEGFC 抗体
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    适用
    • 96
    • 57
    • 38
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 94
    • 28
    • 1
    • 1
    • 1
    小鼠
    克隆类型
    • 99
    • 26
    单克隆
    标记
    • 49
    • 17
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This VEGFC antibody is un-conjugated
    应用范围
    • 115
    • 56
    • 47
    • 26
    • 26
    • 25
    • 14
    • 10
    • 7
    • 7
    • 6
    • 5
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects VEGF-C in Western Blots. No cross-reactivity is shown with VEGF-A.
    纯化方法
    Protein G Affinity Chromatography
    免疫原
    Recombinant Human VEGF-C protein (Cat.-No AR01001PU-N)
    克隆位点
    107F10
    亚型
    IgG2a
    Top Product
    Discover our top product VEGFC Primary Antibody
  • 应用备注
    Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL. Centrifuge vial prior to opening.
    缓冲液
    PBS without preservatives or stabilizers
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store at -20 °C. This product should be stored undiluted.
  • 抗原
    VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
    别名
    VEGF-C / Flt4-L (VEGFC 产品)
    别名
    VEGFC antibody, vegf-c antibody, xvegf-c antibody, Flt4-L antibody, VRP antibody, AW228853 antibody, VEGF-C antibody, vascular endothelial growth factor c antibody, vascular endothelial growth factor C antibody, vascular endothelial growth factor C S homeolog antibody, vegfc antibody, VEGFC antibody, vegfc.S antibody, Vegfc antibody
    背景
    VEGF-C, also known as Vascular Endothelial Growth Factor Related Protein (VRP), is a recently discovered VEGF growth factor family member that is most closely related to VEGF-D. The human VEGF-C cDNA encodes a pre-pro-protein of 416 amino acids residues. It is almost identical to the mouse VEGF-C protein. Similar to VEGF-D, VEGF-C has a VEGF homology domain spanning the middle third of the precursor molecule and long N- and C-terminal extensions. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. Recombinant human VEGF-C, lacking the N- and C-terminal extensions and containing only the middle VEGF homology domain, forms primarily non-covalently linked dimers. This protein is a ligand for both VEGFR-2/KDR and VEGFR-3/FLT-4. Since VEGFR-3 is strongly expressed in lymphatic endothelial cells, it has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. Although recombinant human VEGF-C is also a mitogen for vascular endothelial cells, it is much less potent than VEGF-A. The recombinant human VEGF-C contains 115 amino acids residues and was fused to a His-tag (6x His) at the C-terminal end. As a result of glycosylation VEGF-C migrates as an 18-24 kDa protein in SDS-PAGE under reducing conditions.Synonyms: Flt4 ligand, VEGFC, VRP, Vascular endothelial growth factor C, Vascular endothelial growth factor-related protein
    基因ID
    7424
    NCBI登录号
    NP_005420
    UniProt
    P49767
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
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