DUSP1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for DUSP1 抗体 (N-Term) (ABIN360822)
抗原
See all DUSP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody reacts to DUSP1.
-
纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
-
免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP1.
-
亚型
- Ig Fraction
-
-
anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibody
Verified DUSP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 151-250) antibodyDUSP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (Ser296), (Ser318) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 305-367) antibodyDUSP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibodyDUSP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 305-367) antibodyDUSP1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (pSer296), (pSer318) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (Ser31) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 87-101), (C-Term) antibodyDUSP1 适用: 人, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS with 0.09 % (W/V) sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
-
别名
- DUSP1 / MKP1
-
背景
- The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein hasintrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.Synonyms: CL100, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, MAP kinase phosphatase 1, MKP-1, PTPN10, Protein-tyrosine phosphatase CL100, VH1
-
基因ID
- 1843, 9606
-
UniProt
- P28562
抗原
-
