DUSP10 抗体 (N-Term)
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Quick Overview for DUSP10 抗体 (N-Term) (ABIN360788)
抗原
See all DUSP10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to DUSP10.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DUSP10.
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亚型
- Ig Fraction
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anti-Dual Specificity Phosphatase 10 (DUSP10) (AA 1-140) antibody
DUSP10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (Internal Region) antibodyDUSP10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (C-Term) antibodyDUSP10 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (AA 1-30), (N-Term) antibodyDUSP10 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB5879 unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (AA 1-300) antibodyDUSP10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (AA 204-232) antibodyDUSP10 适用: 人 WB 宿主: 兔 Polyclonal RB41917 unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (C-Term) antibodyDUSP10 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (C-Term) antibodyVerified DUSP10 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (C-Term) antibodyDUSP10 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 10 (DUSP10) (AA 330-410) antibodyDUSP10 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
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别名
- DUSP10 / MKP5
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背景
- Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique, it is evenly distributed in both the cytoplasm and the nucleus. The protein is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli.Synonyms: Dual specificity protein phosphatase 10, MAP kinase phosphatase 5, MKP-5, Mitogen-activated protein kinase phosphatase 5
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基因ID
- 11221, 9606
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UniProt
- Q9Y6W6
抗原
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