DUSP8 抗体 (C-Term)
Quick Overview for DUSP8 抗体 (C-Term) (ABIN360785)
抗原
See all DUSP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to DUSP8.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DUSP8.
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亚型
- Ig Fraction
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anti-Dual Specificity Phosphatase 8 (DUSP8) antibody
DUSP8 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) antibodyDUSP8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (N-Term) antibodyVerified DUSP8 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (AA 359-408) antibodyDUSP8 适用: 人, 小鼠, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (Middle Region) antibodyDUSP8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 8 (DUSP8) (AA 456-487), (C-Term) antibodyDUSP8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5874 unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
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背景
- DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8 inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.Synonyms: Dual specificity protein phosphatase 8
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基因ID
- 1850, 9606
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UniProt
- Q13202
抗原
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