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DUSP6 抗体 (Middle Region)

DUSP6 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360781
发货至: 中国
  • 抗原 See all DUSP6 抗体
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    抗原表位
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 90
    • 59
    • 52
    • 2
    • 1
    • 1
    宿主
    • 78
    • 11
    • 2
    • 1
    克隆类型
    • 73
    • 19
    多克隆
    标记
    • 40
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP6 antibody is un-conjugated
    应用范围
    • 63
    • 35
    • 15
    • 13
    • 11
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to DUSP6.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human DUSP6.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP6 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    DUSP6 (Dual Specificity Phosphatase 6 (DUSP6))
    别名
    DUSP6 (DUSP6 产品)
    别名
    HH19 antibody, MKP3 antibody, PYST1 antibody, 1300019I03Rik antibody, MKP-3 antibody, Mkp3 antibody, wu:fd99d09 antibody, mkp3 antibody, pyst1 antibody, DUSP6 antibody, dusp6 antibody, dual specificity phosphatase 6 antibody, dual specificity phosphatase 6 L homeolog antibody, Dual specificity protein phosphatase 6 antibody, DUSP6 antibody, Dusp6 antibody, dusp6 antibody, dusp6.L antibody, dus6 antibody
    背景
    DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Twotranscript variants encoding different isoforms have been found for the DUSP6 gene.Synonyms: Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, MKP3, Mitogen-activated protein kinase phosphatase 3, PYST1
    基因ID
    1848, 9606
    UniProt
    Q16828
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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