Hexokinase 1 抗体 (N-Term)
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Quick Overview for Hexokinase 1 抗体 (N-Term) (ABIN360644)
抗原
See all Hexokinase 1 (HK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody reacts to HK1.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HK1.
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亚型
- Ig Fraction
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anti-Hexokinase 1 (HK1) (AA 413-540) antibody
HK1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) antibodyKO Validated HK1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Hexokinase 1 (HK1) (AA 20-300) antibodyHK1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) (AA 1-916) antibodyHK1 适用: 人 WB, IP, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) antibodyHK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3A10 unconjugated
anti-Hexokinase 1 (HK1) (AA 78-108), (N-Term) antibodyHK1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3921-RB3922 unconjugated
anti-Hexokinase 1 (HK1) antibodyHK1 适用: 人 WB, ICC, IF, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 1 (HK1) antibodyHK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-Hexokinase 1 (HK1) (AA 1-917), (N-Term) antibodyHK1 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Hexokinase 1 (HK1) (AA 80-215) antibodyHK1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Hexokinase 1 (HK1)
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别名
- Hexokinase-1
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背景
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. The hexokinase gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of the hexokinase gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. HK1 encodes the ubiquitously expressed isoform. Its 5' end includes an exon which is unique to this transcript and which encodes a distinct N-terminus that contains the porin binding domain (PBD). The porin binding domain mediates association with the mitochondrial membrane.Synonyms: Brain form hexokinase, HK1, Hexokinase type I
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基因ID
- 3098, 9606
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UniProt
- P19367
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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