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PFKM 抗体 (N-Term)

This anti-PFKM antibody is a 兔 多克隆 antibody detecting PFKM in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN360632
发货至: 中国
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Quick Overview for PFKM 抗体 (N-Term) (ABIN360632)

抗原

See all PFKM 抗体
PFKM (phosphofructokinase, Muscle (PFKM))

适用

  • 91
  • 50
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  • 9
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宿主

  • 83
  • 9
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克隆类型

  • 65
  • 37
多克隆

标记

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This PFKM antibody is un-conjugated

应用范围

  • 83
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
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    • 1
    • 1
    • 1
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    N-Term

    特异性

    This antibody reacts to PFKM.

    纯化方法

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    免疫原

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PFKM.

    亚型

    Ig Fraction
  • 应用备注

    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原

    PFKM (phosphofructokinase, Muscle (PFKM))

    别名

    PFKM

    背景

    Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.Synonyms: 6-phosphofructokinase muscle type, GSD7, PFK-1, PFK-A, PFK1, PFKX, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphofructokinase-M, Phosphohexokinase

    基因ID

    5213, 9606

    UniProt

    P08237

    途径

    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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