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STK39 抗体 (Middle Region)

STK39 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360385
发货至: 中国
  • 抗原 See all STK39 抗体
    STK39 (serine threonine Kinase 39 (STK39))
    抗原表位
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 76
    • 52
    • 23
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 83
    • 5
    • 1
    克隆类型
    • 81
    • 8
    多克隆
    标记
    • 55
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This STK39 antibody is un-conjugated
    应用范围
    • 69
    • 51
    • 28
    • 15
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to SPAK.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human SPAK.
    亚型
    Ig Fraction
    Top Product
    Discover our top product STK39 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    STK39 (serine threonine Kinase 39 (STK39))
    别名
    STK39 / SPAK (STK39 产品)
    别名
    dcht antibody, pask antibody, spak antibody, MGC69537 antibody, DCHT antibody, PASK antibody, SPAK antibody, Spak antibody, AW227544 antibody, AW556857 antibody, RF005 antibody, Rnl5 antibody, serine/threonine kinase 39 antibody, serine/threonine kinase 39 L homeolog antibody, serine threonine kinase 39 antibody, stk39 antibody, STK39 antibody, stk39.L antibody, Stk39 antibody
    背景
    SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas. SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SPAK. SPAK activates the p38 MAP kinase pathway in cotransfection assays. Full-length SPAK is expressed in the cytoplasm in transfected cells, while a mutant corresponding to caspase-cleaved STK39 localizes predominantly in the nucleus.Synonyms: DCHT, STE20/SPS1-related proline-alanine-rich protein kinase, Serine/threonine-protein kinase 39, Ste-20-related kinase
    基因ID
    27347, 9606
    UniProt
    Q9UEW8
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