STK39 抗体 (Middle Region)
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北京 101111
Quick Overview for STK39 抗体 (Middle Region) (ABIN360385)
抗原
See all STK39 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody reacts to SPAK.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human SPAK.
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亚型
- Ig Fraction
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anti-serine threonine Kinase 39 (STK39) (AA 346-376) antibody
STK39 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03418 unconjugated
anti-serine threonine Kinase 39 (STK39) antibodySTK39 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Internal Region) antibodyVerified STK39 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (AA 425-450) antibodySTK39 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) antibodyKD Validated STK39 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3395 unconjugated Recombinant Antibody
anti-serine threonine Kinase 39 (STK39) (AA 63-545) antibodySTK39 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Ser325) antibodySTK39 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (Ser311) antibodySTK39 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (pSer311) antibodySTK39 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine threonine Kinase 39 (STK39) (AA 375-425) antibodySTK39 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- STK39 (serine threonine Kinase 39 (STK39))
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别名
- STK39 / SPAK
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背景
- SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas. SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SPAK. SPAK activates the p38 MAP kinase pathway in cotransfection assays. Full-length SPAK is expressed in the cytoplasm in transfected cells, while a mutant corresponding to caspase-cleaved STK39 localizes predominantly in the nucleus.Synonyms: DCHT, STE20/SPS1-related proline-alanine-rich protein kinase, Serine/threonine-protein kinase 39, Ste-20-related kinase
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基因ID
- 27347, 9606
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UniProt
- Q9UEW8
抗原
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